Development of a fluorescence sensing assay based on N–S‑doped carbon dots and molecularly imprinted polymer for selective and sensitive detection of florfenicol in milk

Development of a fluorescence sensing assay based on N–S‑doped carbon dots and molecularly imprinted polymer for selective and sensitive detection of florfenicol in milk


چاپ صفحه
پژوهان
صفحه نخست سامانه
چکیده مقاله
چکیده مقاله
نویسندگان
نویسندگان
مؤسسه علوم و صنایع غذایی
مؤسسه علوم و صنایع غذایی

نویسندگان: جواد فیضی , مسلم جهانی

نشریه: Journal of the Iranian Chemical Society , 2 , 20 , 2023

اطلاعات کلی مقاله
hide/show

کد مقاله 2090
عنوان فارسی مقاله Development of a fluorescence sensing assay based on N–S‑doped carbon dots and molecularly imprinted polymer for selective and sensitive detection of florfenicol in milk
عنوان لاتین مقاله Development of a fluorescence sensing assay based on N–S‑doped carbon dots and molecularly imprinted polymer for selective and sensitive detection of florfenicol in milk
نمایه علمی معتبر JCR
IF 2.271
عنوان نشریه Journal of the Iranian Chemical Society
شماره نشریه 2
دوره 20
سال انتشار شمسی 1401/11/12
سال انتشار میلادی 2023

خلاصه مقاله
hide/show

Antibiotic residues can cause serious health risks by contaminating products for human consumption, such as meat and milk. The present study developed a reliable and sensitive method based on spectrofluorometric detections to determine Florfenicol (FF) residues in milk samples. N–S co-doped carbon dots (CDs) were synthesized through a fast and straightforward microwave-assisted method with tri-ammonium citrate as precursor and thiourea as the sulfur source. The synthesis was performed under microwave irradiation at 400 W for 2.5 min. The CDs were incorporated into a molecularly imprinted polymer (MIP) prepared with (3-aminopropyl)triethoxysilane and tetraethoxysilane as the monomer and crosslinker, respectively. The CDs@MIP composite demonstrated excellent fluorescence stability with specific binding sites, which selectively accumulated FF as the target analyte and was used as a selective sensor for the fluorometric determination of FF. The photoluminescence intensity of the CDs@MIP composite was quenched in the presence of FF but not with other drugs or substances. This fact indicates the selective behavior of the new material toward FF as the template. Under optimal conditions, the relative fluorescence intensity of MIP-coated CDs decreased linearly with increasing the concentration of FF from 3.00 μmol L− 1 to 1.50 × 102 μmol L− 1, and its detection limit was 1.11 μmol L− 1. The new sensor was evaluated for FF detection in spiked milk samples and showed recoveries of 90.86–97.71%. The method proposed the advantages of simplicity, sensitivity, selectivity, and low cost.

نویسندگان
hide/show

نویسنده نفر چندم مقاله
جواد فیضیدوم
مسلم جهانیاول